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Two tablets of lopinavir and ritonavir Medication, what is it? Both LOPINAVIR and RITONAVIR are antiviral drugs that stop the HIV cells from dividing in your body. One treatment for HIV, the virus that causes AIDS, is a combination drug called Kaletra, which contains lopinavir and ritonavir. The HIV/AIDS virus cannot be cured with this medication. In addition to the uses described in this medication guide, Kaletra may be used for other purposes. What information is necessary for my doctor to have before prescribing this medication? Lopinavir and ritonavir have the potential to cause serious drug interactions with other medications. It is important to inform all of your healthcare providers about the medications you are currently taking, as well as any new or changed medications. Using some medications with Kaletra might lead to undesirable or even harmful side effects. Do not use alfuzosin, pimozide, rifampin, lovastatin, simvastatin, midazolam, triazolam, sildenafil (Revatio for pulmonary arterial hypertension), St. John's wort, or any ergot medicine; your doctor may need to change your treatment plan because of this. Be sure to inform your doctor about any of the following conditions before starting Kaletra: hepatitis B or C, heart disease, pancreas problems, diabetes, low potassium levels, bleeding disorders like hemophilia, high cholesterol, triglycerides, or a history of using protease inhibitors. This will help ensure that Kaletra is safe for you to use. Whether this medication is harmful to a developing fetus is unknown. Negligible treatment during pregnancy increases the risk of HIV transmission to the unborn child. To manage your HIV infection, take all of your medications as prescribed. Your name may be added to a pregnancy register if you are expecting a child. The goal is to monitor the pregnancy's progress and determine whether Kaletra has any negative impacts on the unborn child. Kaletra can reduce the efficacy of oral contraceptives. To avoid becoming pregnant while taking Kaletra, see your doctor about the use of a non-hormone birth control technique. This may be a diaphragm, spermicide, condom, or other similar device. It is unwise for women living with HIV or AIDS to nurse their infants. The risk of HIV transmission to a newborn through breast milk exists even in cases when the virus is not present at birth. Anyone less than fourteen days old should not use Kaletra. Wait until fourteen days after the baby's actual due date before giving them the medicine if they were born prematurely. Tell me how to use this medication. When administering medication to a kid, it is extremely important to follow all instructions on the prescription label. Never exceed the prescribed dosage or duration of use of this medication. Make sure to inform your doctor if your kid has any changes in weight while taking this medicine. Doses of Kaletra for children are determined by their weight. Keep a Kaletra tablet whole; do not break, crush, or chew it. Give the tablet a full swallow. It is not necessary to eat before or after taking a Kaletra pill. Regular visits to the doctor for blood testing may be necessary while taking Kaletra. Treatment for HIV/AIDS often involves a mix of medications. Take every prescription exactly as prescribed. Each medicine comes with a set of directions for use or a medication guide that you should read carefully. Without your doctor's approval, do not alter the frequency or dosage of your prescription. Those living with HIV or AIDS should always have a doctor at their side. How about potential drug interactions? Kaletra has the potential to interact with a wide variety of medicines. The following list does not include all potential interactions. Notify your doctor of any new or changed medications you are taking, particularly: antiviral medicines to treat hepatitis C or HIV; cancer medicine; medicine to prevent organ transplant rejection; "statin" cholesterol-lowering medicine; an antibiotic--bedaquiline, clarithromycin, metronidazole, rifabutin; antifungal medicine--itraconazole, ketoconazole, voriconazole; heart or blood pressure medicine--amiodarone, felodipine, lidocaine, nicardipine, nifedipine, quinidine; medicine to prevent blood clots--rivaroxaban, warfarin (Coumadin, Jantoven); medicine to treat impotence or pulmonary arterial hypertension--avanafil (Stendra), sildenafil (Viagra, Revatio), tadalafil (Adcirca, Cialis), or vardenafil (Levitra, Staxyn); medicine to treat severe depression or schizophrenia--bupropion (Wellbutrin, Zyban), quetiapine, trazodone; narcotic medicine--fentanyl, methadone; seizure Many more medications may interact with Kaletra; this list is by no means exhaustive. All medications, both OTC and prescribed, as well as nutritional supplements and herbal remedies, fall under this category. If you see more than one doctor, they will need a complete inventory of your medications. While using this medication, what am I to look out for? There is no evidence that this medicine can stop you from transmitting HIV to others. Have intercourse while wearing protection and never share a razor or toothbrush. Discuss safe methods of preventing the spread of HIV during sexual activity with your doctor. No one, no matter how healthy they are, should ever share a needle for a drug or prescription. In what ways may this medication affect my body? Immediate medical assistance is required in the event of an allergic reaction: reaction symptoms include a swollen face, lips, tongue, or throat as well as hives and trouble breathing. Stop taking Kaletra and call your doctor at once if you have: headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats; severe pain in your upper stomach spreading to your back, nausea and vomiting; itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); high blood sugar (increased thirst, increased urination); penis erection that is painful or lasts 4 hours or longer (if you take Kaletra with erectile dysfunction medication); muscle weakness, tired feeling, joint or muscle pain, feeling short of breath; or severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blist Because it alters the function of the immune system, kaletra may raise the risk of certain infections or autoimmune diseases. Kaletra side effects might manifest anywhere from a few weeks to a few months after therapy begins. Notify your doctor if you experience any of the following symptoms: fever, night sweats, swollen glands, mouth sores, diarrhea, stomach pain, weight loss, chest pain (especially when breathing), dry cough, wheezing, difficulty breathing, cold sores, sores on the genital or anal area, rapid heart rate, anxiety, irritability, weakness, prickly feeling, problems with balance or eye movement, trouble speaking or swallowing, severe lower back pain, loss of bladder or bowel control, swelling in the neck or throat (enlarged thyroid), menstrual changes, impotence, or lack of interest in sexual relations. Side effects such as nausea, vomiting, diarrhea, elevated cholesterol, or changes in body fat distribution (particularly in certain areas such as the waist, arms, legs, face, and neck) are common. Just where should I put my medication? The pills should be kept dry and at room temperature. Be sure to seal the pill container after each use.